This course begins with a review of routes of administration, ADME (absorption, distribution, metabolism, & excretion), and the use of in vivo drug concentration-time data to determine key pharmacokinetic parameters, like volume of distribution, half-life and clearance. The course then emphasizes in vitro assays that allow rapid prediction of ADME and PK properties for evaluation of new compounds. The later stages of the course focus on how drug discovery teams study this PK/PD relationship, as well as dose size and frequency predictions which ultimately assist in selection of a compound for advancement into the clinic.
Pharmacokinetics
Pharmacokinetics
This course is part of Drug Hunting: The Science of Making New Medicines Specialization
Instructors: Erland Stevens, PhD
4,253 already enrolled
Included with 
Gain insight into a topic and learn the fundamentals.
4.9
(48 reviews)
Intermediate level
Recommended experience
Flexible schedule
Approx. 12 hours
Learn at your own pace
Earn a Certificate
With paid plans
Skills you'll gain
Details to know
Shareable certificate
Add to your LinkedIn profile
Assessments
15 assignments
Taught in English
See how employees at top companies are mastering in-demand skills
Build your subject-matter expertise
This course is part of the Drug Hunting: The Science of Making New Medicines Specialization
When you enroll in this course, you'll also be enrolled in this Specialization.
- Learn new concepts from industry experts
- Gain a foundational understanding of a subject or tool
- Develop job-relevant skills with hands-on projects
- Earn a shareable career certificate
Earn a career certificate
Add this credential to your LinkedIn profile, resume, or CV
Share it on social media and in your performance review
There are 3 modules in this course
Welcome, by the end of the course students will be able to: Summarize the key concepts of pharmacokinetics (PK), ADME (Absorption, Distribution, Metabolism, and Excretion), volume of distribution, half-life and clearance. Differentiate between different routes of drug administration and their impact on PK parameters. Define and describe the influence of transporters, plasma protein binding (PPB) and drug-drug interactions (DDIs) on the PK of a drug molecule. Explain how PK/PD relationships are derived and their importance for defining the anticipated human dose.
What's included
5 videos1 reading4 assignments
What's included
5 videos1 reading6 assignments
What's included
5 videos1 reading5 assignments
Instructors
Instructor ratings
4.8 (12 ratings)6 Courses8,967 learners
Offered by
Why people choose Coursera for their career
Felipe M.
Learner since 2018
"To be able to take courses at my own pace and rhythm has been an amazing experience. I can learn whenever it fits my schedule and mood."
Jennifer J.
Learner since 2020
"I directly applied the concepts and skills I learned from my courses to an exciting new project at work."
Larry W.
Learner since 2021
"When I need courses on topics that my university doesn't offer, Coursera is one of the best places to go."
Chaitanya A.
"Learning isn't just about being better at your job: it's so much more than that. Coursera allows me to learn without limits."
Learner reviews
4.9
48 reviews
- 5 stars
89.58%
- 4 stars
10.41%
- 3 stars
0%
- 2 stars
0%
- 1 star
0%
Showing 3 of 48
AP
5
Reviewed on Sep 8, 2024
Amazing course for people intending to pursue higher studies in the field of pharmacology
OI
5
Reviewed on Jul 15, 2024
Amazing to-the-point course content, great citations to key articles and questions which are very helpful for permenance. I'm pleased as a medical doctor in drug research. Thanks for this course!
KK
5
Reviewed on Jun 1, 2024
I enjoyed the entire specialization thanks to great bit sized lectures, additional readings, videos and exploratory exercises.
Get access to all these courses and more with a subscription
Novartis
University of California San Diego
Career resources
Unlock access to 10,000+ courses with a subscription
Explore roles and skills, learn more effectively with Coursera Coach, and earn recognized credentials
Advance your career with an online degree
Earn a degree from world-class universities - 100% online
Join over 3,400 global companies that choose Coursera for Business
Upskill your employees to excel in the digital economy
Frequently asked questions
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
The course may not offer an audit option. You can try a Free Trial instead, or apply for Financial Aid.
The course may offer 'Full Course, No Certificate' instead. This option lets you see all course materials, submit required assessments, and get a final grade. This also means that you will not be able to purchase a Certificate experience.
When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.
If you subscribed, you get a 7-day free trial during which you can cancel at no penalty. After that, we don’t give refunds, but you can cancel your subscription at any time. See our full refund policy.
More questions
Financial aid available,